How Do Clinicians Adjust Lamotrigine Doses and Use Lamotrigine Blood Levels?-A Q-PULSE Survey.
نویسندگان
چکیده
منابع مشابه
Lamotrigine toxicity secondary to sertraline
Blood level monitoring helps to determine the therapeutic and toxic ranges for anticonvulsants and antidepressants. We investigated initial drug-drug interactions between lamotrigine and sertraline. We report on case histories of two epileptic patients who were initially on lamotrigine and to whom sertraline was added to control psychiatric features. In case 1, a total daily dose of 25 mg sertr...
متن کاملReport of severe menorrhagia following the maximum amount of lamotrigine overdose
Lamotrigine is an antiepileptic drug used as a treatment for partial and generalised seizures as well as for bipolar disorder type I. Till date, very few cases of lamotrigine overdose have been reported. The spectra of clinical effects of lamotrigine in acute overdose are not well established. In severe cases of poisoning, serious effects such as coma, respiratory depression, recurrent seizures...
متن کاملAre doses of lamotrigine or levetiracetam adjusted during pregnancy?
Subtherapeutic levels of lamotrigine and levetiracetam are more likely to occur during pregnancy owing to the effect of pregnancy on their pharmacokinetics. This can lead to suboptimal control of epilepsy, and guidelines recommend proactive dose adjustment in the second and third trimesters alongside therapeutic drug monitoring (TDM). This retrospective cohort study using administrative databas...
متن کاملReport of severe menorrhagia following the maximum amount of lamotrigine overdose
Lamotrigine is an antiepileptic drug used as a treatment for partial and generalised seizures as well as for bipolar disorder type I. Till date, very few cases of lamotrigine overdose have been reported. The spectra of clinical effects of lamotrigine in acute overdose are not well established. In severe cases of poisoning, serious effects such as coma, respiratory depression, recurrent seizures...
متن کاملEffect of hydroalcoholic extract of ginger on the liver of epileptic female rats treated with lamotrigine
Objective: Lamotrigine is an antiepileptic drug, widely used in the treatment of epilepsy; long-term use of this drug can cause hepatotoxicity. Zingiber officinale Roscoe (ginger) possesses antioxidant properties. In present research, the effect ofhydroalcoholic extract of ginger (HEG) on the liver of lamotrigine-treated epileptic rats was investigated Material and Methods: Forty-eight female W...
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عنوان ژورنال:
- Epilepsy currents
دوره 14 4 شماره
صفحات -
تاریخ انتشار 2014